Baclofen 

Baclofen is a drug used specifically to suppress muscle spasms. It’s a curative agent that effectively works for the treatment of the symptoms of some defects got from sclerosis and spinal cord disorders which may be tenderness, spasm, and stiffness. 

Composition 

Baclofen USP as a crystalline powder with no odor is of different forms of 10mg and 20mg tablets. Its composition is practically from the following ingredients: 

· Colloidal silicon dioxide; 

· Microcrystalline cellulose; 

· Magnesium stearate; 

· Potato starch; 

· Povidone. 

Indication 

There are many cases of spinal cord disorders and multiple sclerosis. Baclofen works effectively as an agent of antispasmodic. It helps with muscles’ relaxation. With this, patients who suffer under critical medical conditions such as spinal cord disease and multiple sclerosis receive Baclofen prescription. 

Mode of Indication, Dosage, and Duration of Treatment 

Ensure you adhere to every prescriptive instruction given by your doctor or given on the prescription label. Before taking Baclofen, shake it well then measure using spoon, syringe or any other available measuring objects for you to get the accurate amount of the drug to be taken. Following your doctor’s direction, you may be told to take Baclofen in a day 3 times with or without a meal. Take note that increasing dose may depend on medical condition; so, don’t increase the dosage without informing your doctor or prescriber. Beware of a sudden pullback. This may result in a seizure or hallucinations. Let your doctor decide when to safely withdraw from its use. Notify your doctor in case there is no improvement in muscle symptoms or if there is deterioration.  

Precautions 

The following precautionary measures must be taken in order to be free from some possible severe side effects: 

· Patients who are allergic to Baclofen should keep away from their use.  

· Notify your doctor if you have any record on illnesses such as ulcers, kidney disease, seizure disorder, mental disorders, Parkinson’s disease, hypertension, diabetes,  

· Pregnant women and lactating mothers should notify their doctors about their conditions. 

· Children from the age of 12 downward are restricted from Baclofen use. 

Side Effects 

Ensure you desist from the use of Baclofen when you sense any allergic reactions such as your lips, tongue, throat or face swelling up; hives; and difficulty in breathing. Moreover, quickly see your doctor or call for medical help when you start to experience any of the side effects. The following are some of the common side effects of Baclofen: 

· Headache; 

· Weakness; 

· Dizziness; 

· Drowsiness; 

· Insomnia; 

· Nausea; 

· Abnormal urination. 

Missed Dose 

The missed dose can be taken when recollected. However, ensure you mind the next time of usage for you not to take it in proximity with the next dose. You are advised not to take more than of the drug required. 

Overdose 

Peradventure you take more than the number of doses required; you should call for emergency or quickly go see your doctor.  The overdose of Baclofen comes with side effects such as: 

· Vomiting; 

· Drowsiness; 

· Breathing difficulty; 

· Coma; 

· Seizure; 

· Dilated pupils; 

· Muscle weakness. 

Contraindication 

Hypersensitive patients should mind their allergic reactions to Baclofen. Those that react to Baclofen are restricted from its use. 

Interaction with Other Drugs 

It is advisable to seek the direction of your doctor before starting a new medication or before interacting Baclofen with other drugs. You must ensure you don’t use Baclofen with alcohol as it may result in depression of CNS (Central Nervous System) and RS (Respiratory Systems). It leads to dizziness and concentration difficulty. Make thorough inquiries from your doctor on the following drugs if you can interact them with Baclofen (as it may result in severe side effects if wrongly administered): 

· Opioids; 

· Antihypertensives; 

· Clobazam.